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Structure paper

Titlealpha beta T-cell receptor recognition of self-phosphatidylinositol presented by CD1b.
Journal, issue, pagesJ. Biol. Chem., Vol. 299, Page 102849-102849, Year 2023
Publish dateJul 28, 2022 (structure data deposition date)
AuthorsFarquhar, R. / Van Rhijn, I. / Moody, D.B. / Rossjohn, J. / Shahine, A.
External linksJ. Biol. Chem. / PubMed:36587766
MethodsX-ray diffraction
Resolution1.9 - 2.4 Å
Structure data

PDB-8dv3:
Crystal structure of human CD1b presenting Phosphatidylinositol C34:1
Method: X-RAY DIFFRACTION / Resolution: 1.9 Å

PDB-8dv4:
Crystal structure of the BC8B TCR-CD1b-PI complex
Method: X-RAY DIFFRACTION / Resolution: 2.4 Å

Chemicals

ChemComp-EDO:
1,2-ETHANEDIOL

ChemComp-CL:
Unknown entry

ChemComp-NA:
Unknown entry

ChemComp-6UL:
TETRACOSYL PALMITATE

ChemComp-IOD:
IODIDE ION

ChemComp-PIE:
1,2-DIACYL-SN-GLYCERO-3-PHOSPHOINOSITOL

ChemComp-HOH:
WATER

ChemComp-GOL:
GLYCEROL

ChemComp-MAN:
alpha-D-mannopyranose

ChemComp-NAG:
2-acetamido-2-deoxy-beta-D-glucopyranose

ChemComp-CUY:
tetracosyl octadecanoate

Source
  • homo sapiens (human)
KeywordsIMMUNE SYSTEM / Antigen presentation / lipid / TCR / autoreactivity

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