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Structure paper

TitleStructural basis of transition from initiation to elongation in de novo viral RNA-dependent RNA polymerases.
Journal, issue, pagesProc. Natl. Acad. Sci. USA, Vol. 120, Page e2211425120-e2211425120, Year 2023
Publish dateMar 26, 2022 (structure data deposition date)
AuthorsWu, J. / Wang, X. / Liu, Q. / Lu, G. / Gong, P.
External linksProc. Natl. Acad. Sci. USA / PubMed:36577062
MethodsX-ray diffraction
Resolution2.58 - 2.85 Å
Structure data

PDB-7xd8:
Crystal Structure of Dengue Virus Serotype 2 (DENV2) Polymerase Elongation Complex (Native Form)
Method: X-RAY DIFFRACTION / Resolution: 2.85 Å

PDB-7xd9:
Crystal Structure of Dengue Virus serotype 2 (DENV2) Polymerase Elongation Complex (CTP Form)
Method: X-RAY DIFFRACTION / Resolution: 2.58 Å

Chemicals

ChemComp-ZN:
Unknown entry

ChemComp-GOL:
GLYCEROL

ChemComp-HOH:
WATER

ChemComp-MG:
Unknown entry

ChemComp-CTP:
CYTIDINE-5'-TRIPHOSPHATE

Source
  • dengue virus 2
  • synthetic construct (others)
KeywordsTRANSFERASE/RNA / RNA-dependent RNA polymerase / de novo synthesis / elongation complex / priming element / TRANSFERASE / TRANSFERASE-RNA complex

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