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TitleCrystal structure of a pre-chemistry viral RNA-dependent RNA polymerase suggests participation of two basic residues in catalysis.
Journal, issue, pagesNucleic Acids Res., Vol. 50, Page 12389-12399, Year 2022
Publish dateDec 10, 2021 (structure data deposition date)
AuthorsLi, R. / Wang, M. / Gong, P.
External linksNucleic Acids Res. / PubMed:36477355
MethodsX-ray diffraction
Resolution2.53 Å
Structure data

PDB-7w9s:
Crystal structure of the enterovirus 71 polymerase elongation complex (C1S3 form)
Method: X-RAY DIFFRACTION / Resolution: 2.53 Å

Chemicals

ChemComp-CTP:
CYTIDINE-5'-TRIPHOSPHATE

ChemComp-SO4:
SULFATE ION

ChemComp-ZN:
Unknown entry

ChemComp-MG:
Unknown entry

ChemComp-HOH:
WATER

Source
  • enterovirus a71
  • synthetic construct (others)
KeywordsTRANSFERASE/RNA / polymerase-RNA complex / elongation / TRANSFERASE-RNA COMPLEX

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