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TitleAn anti-CD98 antibody displaying pH-dependent Fc-mediated tumour-specific activity against multiple cancers in CD98-humanized mice.
Journal, issue, pagesNat Biomed Eng, Year 2022
Publish dateNov 6, 2020 (structure data deposition date)
AuthorsTian, X. / Liu, X. / Ding, J. / Wang, F. / Wang, K. / Liu, J. / Wei, Z. / Hao, X. / Li, Y. / Wei, X. ...Tian, X. / Liu, X. / Ding, J. / Wang, F. / Wang, K. / Liu, J. / Wei, Z. / Hao, X. / Li, Y. / Wei, X. / Zhang, H. / Sui, J.
External linksNat Biomed Eng / PubMed:36424464
MethodsX-ray diffraction
Resolution2.806 Å
Structure data

PDB-7df1:
Crystal structure of human CD98 heavy chain extracellular domain in complex with S1-F4 scFv
Method: X-RAY DIFFRACTION / Resolution: 2.806 Å

Source
  • homo sapiens (human)
KeywordsANTITUMOR PROTEIN / Complex / tumor growth / antibody

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