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TitleTandem engagement of phosphotyrosines by the dual SH2 domains of p120RasGAP.
Journal, issue, pagesStructure, Vol. 30, Page 1603-1614.e5, Year 2022
Publish dateJun 24, 2022 (structure data deposition date)
AuthorsStiegler, A.L. / Vish, K.J. / Boggon, T.J.
External linksStructure / PubMed:36417908
MethodsX-ray diffraction
Resolution1.95 Å
Structure data

PDB-8dgq:
Crystal structure of p120RasGAP SH2-SH3-SH2 in complex with p190RhoGAP doubly phosphorylated peptide
Method: X-RAY DIFFRACTION / Resolution: 1.95 Å

Chemicals

ChemComp-MLI:
MALONATE ION

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsSIGNALING PROTEIN / SH2 domain / SH3 domain / phosphotyrosine

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