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-Structure paper
| Title | Dynamic Long-Range Interactions Influence Substrate Binding and Catalysis by Human Histidine Triad Nucleotide-Binding Proteins (HINTs), Key Regulators of Multiple Cellular Processes and Activators of Antiviral ProTides. |
|---|---|
| Journal, issue, pages | Biochemistry, Vol. 61, Page 2648-2661, Year 2022 |
| Publish date | Oct 26, 2021 (structure data deposition date) |
Authors | Strom, A. / Shah, R. / Dolot, R. / Rogers, M.S. / Tong, C.L. / Wang, D. / Xia, Y. / Lipscomb, J.D. / Wagner, C.R. |
External links | Biochemistry / PubMed:36398895 |
| Methods | X-ray diffraction |
| Resolution | 2.27 Å |
| Structure data | ![]() PDB-7q2u: |
| Chemicals | ![]() ChemComp-P6G: ![]() ChemComp-CAC: ![]() ChemComp-PG4: ![]() ChemComp-HOH: |
| Source |
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Keywords | HYDROLASE / histidine triad nucleotide-binding protein / HINT / HIT family / Q62A mutant |
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homo sapiens (human)
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