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Structure paper

TitleTargeting platelet GPVI with glenzocimab: a novel mechanism for inhibition.
Journal, issue, pagesBlood Adv, Vol. 7, Page 1258-1268, Year 2023
Publish dateFeb 10, 2022 (structure data deposition date)
AuthorsBilliald, P. / Slater, A. / Welin, M. / Clark, J.C. / Loyau, S. / Pugniere, M. / Jiacomini, I.G. / Rose, N. / Lebozec, K. / Toledano, E. ...Billiald, P. / Slater, A. / Welin, M. / Clark, J.C. / Loyau, S. / Pugniere, M. / Jiacomini, I.G. / Rose, N. / Lebozec, K. / Toledano, E. / Francois, D. / Watson, S.P. / Jandrot-Perrus, M.
External linksBlood Adv / PubMed:36375047
MethodsX-ray diffraction
Resolution1.902 Å
Structure data

PDB-7r58:
Crystal structure of the GPVI-glenzocimab complex
Method: X-RAY DIFFRACTION / Resolution: 1.902 Å

Chemicals

ChemComp-GOL:
GLYCEROL

ChemComp-CL:
Unknown entry

ChemComp-SCN:
THIOCYANATE ION

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
  • mus musculus (house mouse)
KeywordsBLOOD CLOTTING

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