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Structure paper

TitleAmino-acyl tXNA as inhibitors or amino acid donors in peptide synthesis.
Journal, issue, pagesNucleic Acids Res., Vol. 50, Page 11415-11425, Year 2022
Publish dateMar 10, 2022 (structure data deposition date)
AuthorsRietmeyer, L. / Li De La Sierra-Gallay, I. / Schepers, G. / Dorchene, D. / Iannazzo, L. / Patin, D. / Touze, T. / van Tilbeurgh, H. / Herdewijn, P. / Etheve-Quelquejeu, M. / Fonvielle, M.
External linksNucleic Acids Res. / PubMed:36350642
MethodsX-ray diffraction
Resolution1.49 - 1.71 Å
Structure data

PDB-7z5y:
CRYSTAL STRUCTURE OF WEISSELLA VIRIDESCENS FEMXVV NON-RIBOSOMAL AMINO ACID TRANSFERASE IN COMPLEX WITH A PEPTIDYL-XNA CONJUGATE
Method: X-RAY DIFFRACTION / Resolution: 1.71 Å

PDB-7z5z:
CRYSTAL STRUCTURE OF WEISSELLA VIRIDESCENS FEMXVV NON-RIBOSOMAL AMINO ACID TRANSFERASE IN COMPLEX WITH A PEPTIDYL-XNA CONJUGATE
Method: X-RAY DIFFRACTION / Resolution: 1.49 Å

PDB-7z6a:
CRYSTAL STRUCTURE OF WEISSELLA VIRIDESCENS FEMXVV NON-RIBOSOMAL AMINO ACID TRANSFERASE IN COMPLEX WITH A PEPTIDYL-XNA CONJUGATE
Method: X-RAY DIFFRACTION / Resolution: 1.66 Å

PDB-7z6k:
CRYSTAL STRUCTURE OF WEISSELLA VIRIDESCENS FEMXVV NON-RIBOSOMAL AMINO ACID TRANSFERASE IN COMPLEX WITH A PEPTIDYL-XNA CONJUGATE
Method: X-RAY DIFFRACTION / Resolution: 1.6 Å

Chemicals

ChemComp-GOL:
GLYCEROL

ChemComp-UDP:
URIDINE-5'-DIPHOSPHATE / UDP*YM

ChemComp-MUB:
N-acetyl-alpha-muramic acid

ChemComp-HOH:
WATER

Source
  • weissella viridescens (bacteria)
  • synthetic construct (others)
KeywordsTRANSFERASE / FEMX / Xeno-nucleic acids / PEPTIDOGLYCAN / PEPTIDYL-XNA CONJUGATE / TRANSFERASE-PEPTIDE-XNA COMPLEX

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