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TitleSelective degradation of tRNASer(AGY) is the primary driver for mitochondrial seryl-tRNA synthetase-related disease.
Journal, issue, pagesNucleic Acids Res., Vol. 50, Page 11755-11774, Year 2022
Publish dateJul 4, 2022 (structure data deposition date)
AuthorsYu, T. / Zhang, Y. / Zheng, W.Q. / Wu, S. / Li, G. / Li, N. / Yao, R. / Fang, P. / Wang, J. / Zhou, X.L.
External linksNucleic Acids Res. / PubMed:36350636
MethodsX-ray diffraction
Resolution2.8 - 3.2 Å
Structure data

PDB-7ydf:
Crystal structure of human SARS2 catalytic domain
Method: X-RAY DIFFRACTION / Resolution: 2.8 Å

PDB-7ydg:
Crystal structure of human SARS2 catalytic domain with a disease related mutation
Method: X-RAY DIFFRACTION / Resolution: 3.2 Å

Source
  • homo sapiens (human)
KeywordsLIGASE / mitochondrial Seryl-tRNA synthetase

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