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| Title | Hotspot mutations in the structured ENL YEATS domain link aberrant transcriptional condensates and cancer. |
|---|---|
| Journal, issue, pages | Mol. Cell, Vol. 82, Page 4080-4098.e12, Year 2022 |
| Publish date | Feb 25, 2021 (structure data deposition date) |
Authors | Song, L. / Yao, X. / Li, H. / Peng, B. / Boka, A.P. / Liu, Y. / Chen, G. / Liu, Z. / Mathias, K.M. / Xia, L. ...Song, L. / Yao, X. / Li, H. / Peng, B. / Boka, A.P. / Liu, Y. / Chen, G. / Liu, Z. / Mathias, K.M. / Xia, L. / Li, Q. / Mir, M. / Li, Y. / Wan, L. |
External links | Mol. Cell / PubMed:36272410 |
| Methods | X-ray diffraction |
| Resolution | 1.91 - 2.9 Å |
| Structure data | ![]() PDB-7e74: ![]() PDB-7x88: ![]() PDB-7x8b: ![]() PDB-7x8f: ![]() PDB-7x8g: |
| Chemicals | ![]() ChemComp-HOH: ![]() ChemComp-CIT: ![]() ChemComp-CL: |
| Source |
|
Keywords | TRANSCRIPTION / YEATS domain / Complex / histone / GENE REGULATION |
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