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-Structure paper
Title | Development of [1,2]oxazoloisoindoles tubulin polymerization inhibitors: Further chemical modifications and potential therapeutic effects against lymphomas. |
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Journal, issue, pages | Eur. J. Med. Chem., Vol. 243, Page 114744-114744, Year 2022 |
Publish date | Jun 29, 2022 (structure data deposition date) |
Authors | Barreca, M. / Spano, V. / Rocca, R. / Bivacqua, R. / Abel, A.C. / Maruca, A. / Montalbano, A. / Raimondi, M.V. / Tarantelli, C. / Gaudio, E. ...Barreca, M. / Spano, V. / Rocca, R. / Bivacqua, R. / Abel, A.C. / Maruca, A. / Montalbano, A. / Raimondi, M.V. / Tarantelli, C. / Gaudio, E. / Cascione, L. / Rinaldi, A. / Bai, R. / Steinmetz, M.O. / Prota, A.E. / Alcaro, S. / Hamel, E. / Bertoni, F. / Barraja, P. |
External links | Eur. J. Med. Chem. / PubMed:36242921 |
Methods | X-ray diffraction |
Resolution | 2.294 - 2.304 Å |
Structure data | PDB-8a9t: PDB-8a9z: |
Chemicals | ChemComp-GTP: ChemComp-MG: ChemComp-CA: ChemComp-GDP: ChemComp-MES: ChemComp-LNU: ChemComp-IMD: ChemComp-ACP: ChemComp-HOH: ChemComp-LO9: |
Source |
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Keywords | CELL CYCLE / TUBULIN FOLD / CYTOSKELETON / MICROTUBULE |