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TitleTryptophan mutations in G3BP1 tune the stability of a cellular signaling hub by weakening transient interactions with Caprin1 and USP10.
Journal, issue, pagesJ. Biol. Chem., Vol. 298, Page 102552-102552, Year 2022
Publish dateSep 1, 2021 (structure data deposition date)
AuthorsSheehan, C.T. / Hampton, T.H. / Madden, D.R.
External linksJ. Biol. Chem. / PubMed:36183834
MethodsX-ray diffraction
Resolution2.36 Å
Structure data

PDB-7s17:
Crystal structure of human G3BP1-NTF2 with three mutations- F15W, F33W, and F124W
Method: X-RAY DIFFRACTION / Resolution: 2.36 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsRNA BINDING PROTEIN / NTF2-like domain / binding mutant

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