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TitleTargeting the ATG5-ATG16L1 Protein-Protein Interaction with a Hydrocarbon-Stapled Peptide Derived from ATG16L1 for Autophagy Inhibition.
Journal, issue, pagesJ. Am. Chem. Soc., Vol. 144, Page 17671-17679, Year 2022
Publish dateNov 25, 2021 (structure data deposition date)
AuthorsCui, J. / Ogasawara, Y. / Kurata, I. / Matoba, K. / Fujioka, Y. / Noda, N.N. / Shibasaki, M. / Watanabe, T.
External linksJ. Am. Chem. Soc. / PubMed:36107218
MethodsX-ray diffraction
Resolution3 Å
Structure data

PDB-7w36:
Crystal structure of human Atg5 complexed with a stapled peptide
Method: X-RAY DIFFRACTION / Resolution: 3 Å

Source
  • homo sapiens (human)
KeywordsLIGASE / Autophagy / Inhibitor / Complex / Stapled peptide

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