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-Structure paper
| Title | A covalent inhibitor of K-Ras(G12C) induces MHC class I presentation of haptenated peptide neoepitopes targetable by immunotherapy. |
|---|---|
| Journal, issue, pages | Cancer Cell, Vol. 40, Page 1060-1069.e7, Year 2022 |
| Publish date | Oct 27, 2020 (structure data deposition date) |
Authors | Zhang, Z. / Rohweder, P.J. / Ongpipattanakul, C. / Basu, K. / Bohn, M.F. / Dugan, E.J. / Steri, V. / Hann, B. / Shokat, K.M. / Craik, C.S. |
External links | Cancer Cell / PubMed:36099883 |
| Methods | X-ray diffraction |
| Resolution | 2 Å |
| Structure data | ![]() PDB-7kkh: |
| Chemicals | ![]() ChemComp-NA: ![]() ChemComp-91S: ![]() ChemComp-HOH: |
| Source |
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Keywords | IMMUNE SYSTEM / ANTITUMOR PROTEIN / Fab / antibody |
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homo sapiens (human)
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