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-Structure paper
Title | Enabling Aromatic Hydroxylation in a Cytochrome P450 Monooxygenase Enzyme through Protein Engineering. |
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Journal, issue, pages | Chemistry, Vol. 28, Page e202201895-e202201895, Year 2022 |
Publish date | Aug 27, 2020 (structure data deposition date) |
![]() | Coleman, T. / Lee, J.Z.H. / Kirk, A.M. / Doherty, D.Z. / Podgorski, M.N. / Pinidiya, D.K. / Bruning, J.B. / De Voss, J.J. / Krenske, E.H. / Bell, S.G. |
![]() | ![]() ![]() |
Methods | X-ray diffraction |
Resolution | 1.268 - 1.825 Å |
Structure data | ![]() PDB-7jxb: ![]() PDB-7tnd: ![]() PDB-7tnf: ![]() PDB-7tnu: ![]() PDB-8d39: |
Chemicals | ![]() ChemComp-VLG: ![]() ChemComp-HEM: ![]() ChemComp-CL: ![]() ChemComp-HOH: ![]() ChemComp-JO4: ![]() ChemComp-Z7Z: ![]() ChemComp-MG: ![]() ChemComp-EH1: ![]() ChemComp-QDB: |
Source |
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![]() | OXIDOREDUCTASE / Cytochrome / P450 / Monooxygenase / Heme / Oxygen Insertion / Cytochrome P450 / aromatic / CYP199A4 / 4-phenylbenzoic acid / CYP199A4 F298V mutant / F298V mutant / 4-cyclohexylbenzoic acid / aromatic substrate |