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TitleInvariant surface glycoprotein 65 of Trypanosoma brucei is a complement C3 receptor.
Journal, issue, pagesNat Commun, Vol. 13, Page 5085-5085, Year 2022
Publish dateAug 19, 2021 (structure data deposition date)
AuthorsMacleod, O.J.S. / Cook, A.D. / Webb, H. / Crow, M. / Burns, R. / Redpath, M. / Seisenberger, S. / Trevor, C.E. / Peacock, L. / Schwede, A. ...Macleod, O.J.S. / Cook, A.D. / Webb, H. / Crow, M. / Burns, R. / Redpath, M. / Seisenberger, S. / Trevor, C.E. / Peacock, L. / Schwede, A. / Kimblin, N. / Francisco, A.F. / Pepperl, J. / Rust, S. / Voorheis, P. / Gibson, W. / Taylor, M.C. / Higgins, M.K. / Carrington, M.
External linksNat Commun / PubMed:36038546
MethodsX-ray diffraction
Resolution2.6 Å
Structure data

PDB-7pi6:
Trypanosoma brucei ISG65 bound to human complement C3d
Method: X-RAY DIFFRACTION / Resolution: 2.6 Å

Chemicals

ChemComp-GOL:
GLYCEROL

ChemComp-PG0:
2-(2-METHOXYETHOXY)ETHANOL / inhibitor, precipitant*YM

ChemComp-HOH:
WATER

Source
  • trypanosoma brucei brucei (strain 927/4 gutat10.1) (eukaryote)
  • homo sapiens (human)
KeywordsIMMUNE SYSTEM / Complement / innate immunity / host-pathogen / sleeping sickness

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