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-Structure paper
Title | Targeting non-alcoholic fatty liver disease: Design, X-ray co-crystal structure and synthesis of 'first-in-kind' inhibitors of serine/threonine kinase25. |
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Journal, issue, pages | Bioorg. Med. Chem. Lett., Vol. 75, Page 128950-128950, Year 2022 |
Publish date | Mar 4, 2022 (structure data deposition date) |
![]() | Kiyeleko, S. / Hocine, S. / Mautino, G. / Kuenemann, M. / Nawrotek, A. / Miallau, L. / Vuillard, L.M. / Mirguet, O. / Kotschy, A. / Hanessian, S. |
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Methods | X-ray diffraction |
Resolution | 1.644 Å |
Structure data | ![]() PDB-7z4v: |
Chemicals | ![]() ChemComp-IB5: ![]() ChemComp-EDO: ![]() ChemComp-HOH: |
Source |
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![]() | ONCOPROTEIN / tumor suppressor / phosphorylation / YAP/TAZ / kinase |