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Structure paper

TitleProcessing oxidatively damaged bases at DNA strand breaks by APE1.
Journal, issue, pagesNucleic Acids Res., Vol. 50, Page 9521-9533, Year 2022
Publish dateNov 18, 2021 (structure data deposition date)
AuthorsWhitaker, A.M. / Stark, W.J. / Freudenthal, B.D.
External linksNucleic Acids Res. / PubMed:36018803
MethodsX-ray diffraction
Resolution1.99 - 2.24 Å
Structure data

PDB-7suv:
APE1 exonuclease substrate complex with 8oxoG opposite A
Method: X-RAY DIFFRACTION / Resolution: 1.99 Å

PDB-7svb:
APE1 exonuclease substrate complex with 8oxoG opposite C
Method: X-RAY DIFFRACTION / Resolution: 2.24 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
  • synthetic construct (others)
KeywordsHYDROLASE/DNA / nuclease / DNA Repair protein / DNA binding protein / HYDROLASE / HYDROLASE-DNA complex

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