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TitlePhen-DC 3 Induces Refolding of Human Telomeric DNA into a Chair-Type Antiparallel G-Quadruplex through Ligand Intercalation.
Journal, issue, pagesAngew. Chem. Int. Ed. Engl., Vol. 61, Page e202207384-e202207384, Year 2022
Publish dateMar 21, 2022 (structure data deposition date)
AuthorsGhosh, A. / Trajkovski, M. / Teulade-Fichou, M.P. / Gabelica, V. / Plavec, J.
External linksAngew. Chem. Int. Ed. Engl. / PubMed:35993443
MethodsNMR (solution)
Structure data

PDB-7z9l:
Phen-DC3 intercalation causes hybrid-to-antiparallel transformation of human telomeric DNA G-quadruplex
Method: SOLUTION NMR

Chemicals

ChemComp-PQ3:
N2,N9-bis(1-methylquinolin-3-yl)-1,10-phenanthroline-2,9-dicarboxamide

Source
  • homo sapiens (human)
KeywordsDNA / G Quadruplex / ligand intercalation / NMR spectroscopy / Mass spectrometry

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