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-Structure paper
Title | In vivo stabilization of a less toxic asparaginase variant leads to a durable antitumor response in acute leukemia. |
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Journal, issue, pages | Haematologica, Vol. 108, Page 409-419, Year 2023 |
Publish date | Mar 4, 2022 (structure data deposition date) |
![]() | Van Trimpont, M. / Schalk, A.M. / De Visser, Y. / Nguyen, H.A. / Reunes, L. / Vandemeulebroecke, K. / Peeters, E. / Su, Y. / Lee, H. / Lorenzi, P.L. ...Van Trimpont, M. / Schalk, A.M. / De Visser, Y. / Nguyen, H.A. / Reunes, L. / Vandemeulebroecke, K. / Peeters, E. / Su, Y. / Lee, H. / Lorenzi, P.L. / Chan, W.K. / Mondelaers, V. / De Moerloose, B. / Lammens, T. / Goossens, S. / Van Vlierberghe, P. / Lavie, A. |
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Methods | X-ray diffraction |
Resolution | 1.75 Å |
Structure data | ![]() PDB-7u6m: |
Chemicals | ![]() ChemComp-ASP: ![]() ChemComp-HOH: |
Source |
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![]() | HYDROLASE / Asparaginase / Albumin binding domain |