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Structure paper

TitleStructural basis for proton coupled cystine transport by cystinosin.
Journal, issue, pagesNat Commun, Vol. 13, Page 4845-4845, Year 2022
Publish dateApr 12, 2022 (structure data deposition date)
AuthorsLobel, M. / Salphati, S.P. / El Omari, K. / Wagner, A. / Tucker, S.J. / Parker, J.L. / Newstead, S.
External linksNat Commun / PubMed:35977944
MethodsX-ray diffraction
Resolution2.329 - 3.372 Å
Structure data

PDB-7zk1:
Crystal structure of cystinosin from Arabidopsis thaliana bound to sybody and nanobody
Method: X-RAY DIFFRACTION / Resolution: 2.65 Å

PDB-7zkw:
Crystal structure of cystinosin from Arabidopsis thaliana in complex with Cystine and sybody
Method: X-RAY DIFFRACTION / Resolution: 3.372 Å

PDB-7zkz:
Crystal structure of cystinosin from Arabidopsis thaliana bound to two nanobodies
Method: X-RAY DIFFRACTION / Resolution: 2.329 Å

Chemicals

ChemComp-HOH:
WATER

ChemComp-IYY:
L-cystine

Source
  • arabidopsis thaliana (thale cress)
  • lama glama (llama)
  • synthetic construct (others)
KeywordsMEMBRANE PROTEIN / Cystinosin; PQ-loop protein; proton coupling; cystine transport

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