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-Structure paper
Title | The First Class of Small Molecules Potently Disrupting the YAP-TEAD Interaction by Direct Competition. |
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Journal, issue, pages | Chemmedchem, Vol. 17, Page e202200303-e202200303, Year 2022 |
Publish date | May 30, 2022 (structure data deposition date) |
![]() | Furet, P. / Bordas, V. / Le Douget, M. / Salem, B. / Mesrouze, Y. / Imbach-Weese, P. / Sellner, H. / Voegtle, M. / Soldermann, N. / Chapeau, E. ...Furet, P. / Bordas, V. / Le Douget, M. / Salem, B. / Mesrouze, Y. / Imbach-Weese, P. / Sellner, H. / Voegtle, M. / Soldermann, N. / Chapeau, E. / Wartmann, M. / Scheufler, C. / Fernandez, C. / Kallen, J. / Guagnano, V. / Chene, P. / Schmelzle, T. |
![]() | ![]() ![]() |
Methods | X-ray diffraction |
Resolution | 2.699 - 2.895 Å |
Structure data | ![]() PDB-8a0u: ![]() PDB-8a0v: |
Chemicals | ![]() ChemComp-MYR: ![]() ChemComp-KMU: ![]() ChemComp-PO4: ![]() ChemComp-HOH: ![]() ChemComp-DMS: ![]() ChemComp-KNE: |
Source |
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![]() | TRANSCRIPTION / Inhibitor / Complex |