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TitleCatalytic potential of a fungal indole prenyltransferase toward beta-carbolines, harmine and harman, and their prenylation effects on antibacterial activity.
Journal, issue, pagesJ. Biosci. Bioeng., Vol. 134, Page 311-317, Year 2022
Publish dateJun 13, 2022 (structure data deposition date)
AuthorsHamdy, S.A. / Kodama, T. / Nakashima, Y. / Han, X. / Morita, H.
External linksJ. Biosci. Bioeng. / PubMed:35931602
MethodsX-ray diffraction
Resolution2.43 Å
Structure data

PDB-7y3v:
Crystal structure of CdpNPT in complex with harmane
Method: X-RAY DIFFRACTION / Resolution: 2.43 Å

Chemicals

ChemComp-PO4:
PHOSPHATE ION

ChemComp-CN9:
1-methyl-9H-pyrido[3,4-b]indole / alkaloid*YM

ChemComp-HOH:
WATER

Source
  • aspergillus fumigatus (mold)
KeywordsTRANSFERASE / prenyltransferases / cyclic dipeptide N-prenyltransferase

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