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TitleThe transcription factor FoxP3 can fold into two dimerization states with divergent implications for regulatory T cell function and immune homeostasis.
Journal, issue, pagesImmunity, Vol. 55, Page 1354-, Year 2022
Publish dateJan 3, 2022 (structure data deposition date)
AuthorsLeng, F. / Zhang, W. / Ramirez, R.N. / Leon, J. / Zhong, Y. / Hou, L. / Yuki, K. / van der Veeken, J. / Rudensky, A.Y. / Benoist, C. / Hur, S.
External linksImmunity / PubMed:35926508
MethodsX-ray diffraction
Resolution3.1 - 4 Å
Structure data

PDB-7tdw:
Structure of FOXP3-DNA complex
Method: X-RAY DIFFRACTION / Resolution: 4 Å

PDB-7tdx:
Structure of FOXP3-DNA complex
Method: X-RAY DIFFRACTION / Resolution: 3.1 Å

Source
  • mus musculus (house mouse)
KeywordsTRANSCRIPTION/DNA / FOXP3 / Dimer / Forkhead / DNA / Treg / TRANSCRIPTION-DNA complex

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