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-Structure paper
Title | Synthesis and direct assay of large macrocycle diversities by combinatorial late-stage modification at picomole scale. |
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Journal, issue, pages | Nat Commun, Vol. 13, Page 3823-3823, Year 2022 |
Publish date | May 23, 2020 (structure data deposition date) |
Authors | Habeshian, S. / Merz, M.L. / Sangouard, G. / Mothukuri, G.K. / Schuttel, M. / Bognar, Z. / Diaz-Perlas, C. / Vesin, J. / Bortoli Chapalay, J. / Turcatti, G. ...Habeshian, S. / Merz, M.L. / Sangouard, G. / Mothukuri, G.K. / Schuttel, M. / Bognar, Z. / Diaz-Perlas, C. / Vesin, J. / Bortoli Chapalay, J. / Turcatti, G. / Cendron, L. / Angelini, A. / Heinis, C. |
External links | Nat Commun / PubMed:35780129 |
Methods | X-ray diffraction |
Resolution | 2.27 Å |
Structure data | PDB-6z48: |
Chemicals | ChemComp-NA: ChemComp-X1V: ChemComp-HOH: |
Source |
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Keywords | HYDROLASE / serine protease / blood clotting factor / inhibition / macrocycle |