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Structure paper

TitleStructural insights into the function-modulating effects of nanobody binding to the integrin receptor alpha M beta 2.
Journal, issue, pagesJ. Biol. Chem., Vol. 298, Page 102168-102168, Year 2022
Publish dateFeb 26, 2021 (structure data deposition date)
AuthorsJensen, R.K. / Pedersen, H. / Lorentzen, J. / Laursen, N.S. / Vorup-Jensen, T. / Andersen, G.R.
External linksJ. Biol. Chem. / PubMed:35738398
MethodsX-ray diffraction
Resolution1.14 - 3.2 Å
Structure data

PDB-7np9:
Structure of the human CR3 - CD11bCD18 specific nanobody hCR3Nb1
Method: X-RAY DIFFRACTION / Resolution: 1.14 Å

PDB-7p2d:
Structure of alphaMbeta2/Cd11bCD18 headpiece in complex with a nanobody
Method: X-RAY DIFFRACTION / Resolution: 3.2 Å

Chemicals

ChemComp-SO4:
SULFATE ION

ChemComp-HOH:
WATER

ChemComp-CA:
Unknown entry

ChemComp-NAG:
2-acetamido-2-deoxy-beta-D-glucopyranose

Source
  • lama glama (llama)
  • homo sapiens (human)
KeywordsIMMUNE SYSTEM / nanobody / antibody / integrin receptor / complement / phagocytosis / inhibitor / adhesion

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