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Structure paper

TitleMitoxantrone stacking does not define the active or inactive state of USP15 catalytic domain.
Journal, issue, pagesJ. Struct. Biol., Vol. 214, Page 107862-107862, Year 2022
Publish dateFeb 4, 2022 (structure data deposition date)
AuthorsPriyanka, A. / Tisi, D. / Sixma, T.K.
External linksJ. Struct. Biol. / PubMed:35605756
MethodsX-ray diffraction
Resolution1.98 Å
Structure data

PDB-7r2g:
USP15 D1D2 in catalytically-competent state bound to mitoxantrone stack (isoform 2)
Method: X-RAY DIFFRACTION / Resolution: 1.98 Å

Chemicals

ChemComp-ZN:
Unknown entry

ChemComp-GOL:
GLYCEROL

ChemComp-MIX:
1,4-DIHYDROXY-5,8-BIS({2-[(2-HYDROXYETHYL)AMINO]ETHYL}AMINO)-9,10-ANTHRACENEDIONE / antineoplastic*YM

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsHYDROLASE / Cysteine protease

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