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-Structure paper
Title | Scaffold modifications to the 4-(4,4-dimethylpiperidinyl) 2,6-dimethylpyridinyl class of HIV-1 allosteric integrase inhibitors. |
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Journal, issue, pages | Bioorg. Med. Chem., Vol. 67, Page 116833-116833, Year 2022 |
Publish date | Feb 24, 2022 (structure data deposition date) |
![]() | Parcella, K. / Patel, M. / Tu, Y. / Eastman, K. / Peese, K. / Gillis, E. / Belema, M. / Dicker, I.B. / McAuliffe, B. / Ding, B. ...Parcella, K. / Patel, M. / Tu, Y. / Eastman, K. / Peese, K. / Gillis, E. / Belema, M. / Dicker, I.B. / McAuliffe, B. / Ding, B. / Falk, P. / Simmermacher, J. / Parker, D.D. / Sivaprakasam, P. / Khan, J.A. / Kish, K. / Lewis, H. / Hanumegowda, U. / Jenkins, S. / Kadow, J.F. / Krystal, M. / Meanwell, N.A. / Naidu, B.N. |
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Methods | X-ray diffraction |
Resolution | 1.839 Å |
Structure data | ![]() PDB-7u2u: |
Chemicals | ![]() ChemComp-KZD: ![]() ChemComp-SO4: ![]() ChemComp-HOH: |
Source |
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![]() | DNA BINDING PROTEIN / viral protein / INTEGRASE |