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Structure paper

TitleVisualization of mutagenic nucleotide processing by Escherichia coli MutT, a Nudix hydrolase.
Journal, issue, pagesProc. Natl. Acad. Sci. USA, Vol. 119, Page e2203118119-e2203118119, Year 2022
Publish dateFeb 12, 2022 (structure data deposition date)
AuthorsNakamura, T. / Yamagata, Y.
External linksProc. Natl. Acad. Sci. USA / PubMed:35594391
MethodsX-ray diffraction
Resolution1.36 - 1.98 Å
Structure data

PDB-7ww5:
Crystal structure of MutT-8-oxo-dGTP complex
Method: X-RAY DIFFRACTION / Resolution: 1.57 Å

PDB-7ww6:
Crystal structure of MutT-8-oxo-dGTP complex: Reaction for 20 min in 5 mM Mn2+
Method: X-RAY DIFFRACTION / Resolution: 1.36 Å

PDB-7ww7:
Crystal structure of MutT-8-oxo-dGTP complex: Reaction for 1 hr in 5 mM Mn2+
Method: X-RAY DIFFRACTION / Resolution: 1.67 Å

PDB-7ww8:
Crystal structure of MutT-8-oxo-dGTP complex: Reaction for 5 hr in 5 mM Mn2+
Method: X-RAY DIFFRACTION / Resolution: 1.64 Å

PDB-7ww9:
Crystal structure of MutT-8-oxo-dGTP complex: Reaction for 1.5 hr in 20 mM Mn2+
Method: X-RAY DIFFRACTION / Resolution: 1.8 Å

PDB-7wwa:
Crystal structure of MutT-8-oxo-dGTP complex: Reaction for 2.5 hr in 20 mM Mn2+
Method: X-RAY DIFFRACTION / Resolution: 1.9 Å

PDB-7x9h:
Crystal structure of MutT-8-oxo-dGTP complex: Reaction for 9 hr using 5 mM Mn2+
Method: X-RAY DIFFRACTION / Resolution: 1.69 Å

PDB-7x9i:
Crystal structure of MutT-8-oxo-dGTP complex: Reaction for 12 hr using 5 mM Mn2+
Method: X-RAY DIFFRACTION / Resolution: 1.9 Å

PDB-7x9j:
Crystal structure of MutT-8-oxo-dGTP complex: Reaction for 24 hr using 5 mM Mn2+
Method: X-RAY DIFFRACTION / Resolution: 1.98 Å

PDB-7x9k:
Crystal structure of MutT-8-oxo-dGTP complex: Reaction for 2 hr using 10 mM Mn2+
Method: X-RAY DIFFRACTION / Resolution: 1.81 Å

PDB-7x9l:
Crystal structure of MutT-8-oxo-dGTP complex: Reaction for 4 hr using 10 mM Mn2+
Method: X-RAY DIFFRACTION / Resolution: 1.82 Å

PDB-7x9n:
Crystal structure of MutT-8-oxo-dGTP complex with three Mg2+ ions: Reaction using Mg2+
Method: X-RAY DIFFRACTION / Resolution: 1.7 Å

PDB-7x9o:
Crystal structure of MutT-8-oxo-dGMP complex with Mg2+ ions: Reaction using Mg2+
Method: X-RAY DIFFRACTION / Resolution: 1.58 Å

Chemicals

ChemComp-8DG:
8-OXO-2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE

ChemComp-NA:
Unknown entry

ChemComp-SO4:
SULFATE ION

ChemComp-HOH:
WATER

ChemComp-MN:
Unknown entry

ChemComp-8OG:
8-OXO-2'-DEOXY-GUANOSINE-5'-MONOPHOSPHATE

ChemComp-MG:
Unknown entry

Source
  • escherichia coli (E. coli)
KeywordsHYDROLASE / Nudix hydrolase

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