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TitleCrystal structure of a constitutive active mutant of adenosine A 2A receptor.
Journal, issue, pagesIucrj, Vol. 9, Page 333-341, Year 2022
Publish dateJun 1, 2021 (structure data deposition date)
AuthorsCui, M. / Zhou, Q. / Xu, Y. / Weng, Y. / Yao, D. / Zhao, S. / Song, G.
External linksIucrj / PubMed:35546802
MethodsX-ray diffraction
Resolution3.8 Å
Structure data

PDB-7ezc:
Adenosine A2a receptor mutant-I92N
Method: X-RAY DIFFRACTION / Resolution: 3.8 Å

Chemicals

ChemComp-UKA:
6-(2,2-diphenylethylamino)-9-[(2R,3R,4S,5S)-5-(ethylcarbamoyl)-3,4-dihydroxy-oxolan-2-yl]-N-[2-[(1-pyridin-2-ylpiperidin-4-yl)carbamoylamino]ethyl]purine-2-carboxamide / agonist*YM

Source
  • homo sapiens (human)
  • escherichia coli (E. coli)
KeywordsSIGNALING PROTEIN / GPCR / Adenosine / agonist / active mutation

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