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TitleFunctional, structural, and molecular characterizations of the leukemogenic driver MEF2D-HNRNPUL1 fusion.
Journal, issue, pagesBlood, Vol. 140, Page 1390-1407, Year 2022
Publish dateFeb 24, 2022 (structure data deposition date)
AuthorsZhang, M. / Zhang, H. / Li, Z. / Bai, L. / Wang, Q. / Li, J. / Jiang, M. / Xue, Q. / Cheng, N. / Zhang, W. ...Zhang, M. / Zhang, H. / Li, Z. / Bai, L. / Wang, Q. / Li, J. / Jiang, M. / Xue, Q. / Cheng, N. / Zhang, W. / Mao, D. / Chen, Z. / Huang, J. / Meng, G. / Chen, S.J.
External linksBlood / PubMed:35544603
MethodsX-ray diffraction
Resolution3.315 Å
Structure data

PDB-7x1n:
Crystal structure of MEF2D-MRE complex
Method: X-RAY DIFFRACTION / Resolution: 3.315 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsTRANSCRIPTION/DNA / Acute lymphoblastic leukemia / MEF2D-fusions / MEF2D-HNRNPUL1 / MEF2D-DNA interaction / leukemogenesis / prognostic markers / TRANSCRIPTION-DNA COMPLEX

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