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TitleIdentification of oleoylethanolamide as an endogenous ligand for HIF-3 alpha.
Journal, issue, pagesNat Commun, Vol. 13, Page 2529-2529, Year 2022
Publish dateAug 21, 2021 (structure data deposition date)
AuthorsDiao, X. / Ye, F. / Zhang, M. / Ren, X. / Tian, X. / Lu, J. / Sun, X. / Hou, Z. / Chen, X. / Li, F. ...Diao, X. / Ye, F. / Zhang, M. / Ren, X. / Tian, X. / Lu, J. / Sun, X. / Hou, Z. / Chen, X. / Li, F. / Zhuang, J. / Ding, H. / Peng, C. / Rastinejad, F. / Luo, C. / Wu, D.
External linksNat Commun / PubMed:35534502
MethodsX-ray diffraction
Resolution2.3 - 2.507 Å
Structure data

PDB-7v7l:
Crystal Structure of the Heterodimeric HIF-3a:ARNT Complex
Method: X-RAY DIFFRACTION / Resolution: 2.3 Å

PDB-7v7w:
Crystal Structure of the Heterodimeric HIF-3a:ARNT Complex with oleoylethanolamide (OEA)
Method: X-RAY DIFFRACTION / Resolution: 2.507 Å

Chemicals

ChemComp-HOH:
WATER

ChemComp-5YM:
(Z)-N-(2-hydroxyethyl)octadec-9-enamide / agonist*YM

Source
  • mus musculus (house mouse)
KeywordsTRANSCRIPTION / Hypoxia-inducible factor / bHLH-PAS

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