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Structure paper

TitleStructural insights into Ras regulation by SIN1.
Journal, issue, pagesProc. Natl. Acad. Sci. USA, Vol. 119, Page e2119990119-e2119990119, Year 2022
Publish dateNov 4, 2021 (structure data deposition date)
AuthorsZheng, Y. / Ding, L. / Meng, X. / Potter, M. / Kearney, A.L. / Zhang, J. / Sun, J. / James, D.E. / Yang, G. / Zhou, C.
External linksProc. Natl. Acad. Sci. USA / PubMed:35522713
MethodsX-ray diffraction
Resolution1.6 - 1.7 Å
Structure data

PDB-7vv8:
Crystal Structure of HRasQ61L(GMPPNP-bound) in complex with the Ras-binding domain(RBD) of SIN1
Method: X-RAY DIFFRACTION / Resolution: 1.7 Å

PDB-7vv9:
Crystal Structure of HRas(GMPPNP-bound) in complex with the Ras-binding domain(RBD) of SIN1
Method: X-RAY DIFFRACTION / Resolution: 1.6 Å

PDB-7vvb:
Crystal Structure of KRas4A(GMPPNP-bound) in complex with the Ras-binding domain(RBD) of SIN1
Method: X-RAY DIFFRACTION / Resolution: 1.7 Å

PDB-7vvg:
Crystal Structure of HRasG12V(GMPPNP-bound) in complex with the Ras-binding domain(RBD) of SIN1
Method: X-RAY DIFFRACTION / Resolution: 1.7 Å

Chemicals

ChemComp-GNP:
PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER / GppNHp, GMPPNP, energy-carrying molecule analogue*YM

ChemComp-MG:
Unknown entry

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsCELL CYCLE / Ras / RBD

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