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-Structure paper
Title | Structure-Based Design of a Novel Class of Autotaxin Inhibitors Based on Endogenous Allosteric Modulators. |
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Journal, issue, pages | J. Med. Chem., Vol. 65, Page 6338-6351, Year 2022 |
Publish date | Feb 23, 2022 (structure data deposition date) |
Authors | Clark, J.M. / Salgado-Polo, F. / Macdonald, S.J.F. / Barrett, T.N. / Perrakis, A. / Jamieson, C. |
External links | J. Med. Chem. / PubMed:35440138 |
Methods | X-ray diffraction |
Resolution | 2.4 Å |
Structure data | PDB-7z0n: |
Chemicals | ChemComp-MAN: ChemComp-ZN: ChemComp-CA: ChemComp-IOD: ChemComp-SCN: ChemComp-NA: ChemComp-GOL: ChemComp-I8K: ChemComp-HOH: |
Source |
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Keywords | HYDROLASE / Autotaxin / ENPP2 / lysophosphatidic acid / steroid / cancer / fibrosis |