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Structure paper

TitleHigh-pressure crystallography shows noble gas intervention into protein-lipid interaction and suggests a model for anaesthetic action.
Journal, issue, pagesCommun Biol, Vol. 5, Page 360-360, Year 2022
Publish dateOct 27, 2021 (structure data deposition date)
AuthorsMelnikov, I. / Orekhov, P. / Rulev, M. / Kovalev, K. / Astashkin, R. / Bratanov, D. / Ryzhykau, Y. / Balandin, T. / Bukhdruker, S. / Okhrimenko, I. ...Melnikov, I. / Orekhov, P. / Rulev, M. / Kovalev, K. / Astashkin, R. / Bratanov, D. / Ryzhykau, Y. / Balandin, T. / Bukhdruker, S. / Okhrimenko, I. / Borshchevskiy, V. / Bourenkov, G. / Mueller-Dieckmann, C. / van der Linden, P. / Carpentier, P. / Leonard, G. / Gordeliy, V. / Popov, A.
External linksCommun Biol / PubMed:35422073
MethodsX-ray diffraction
Resolution1.65 - 2.6 Å
Structure data

PDB-7q35:
Crystal structure of the mutant bacteriorhodopsin pressurized with krypton
Method: X-RAY DIFFRACTION / Resolution: 2 Å

PDB-7q36:
Crystal structure of KR2 sodium pump rhodopsin pressurized with krypton
Method: X-RAY DIFFRACTION / Resolution: 2.6 Å

PDB-7q37:
Crystal structure of proton pump MAR rhodopsin pressurized with krypton
Method: X-RAY DIFFRACTION / Resolution: 2.25 Å

PDB-7q38:
Crystal structure of the mutant bacteriorhodopsin pressurized with argon
Method: X-RAY DIFFRACTION / Resolution: 1.65 Å

Chemicals

ChemComp-RET:
RETINAL

ChemComp-LFA:
EICOSANE

ChemComp-OLA:
OLEIC ACID

ChemComp-HEX:
HEXANE

ChemComp-SO4:
SULFATE ION

ChemComp-KR:
KRYPTON

ChemComp-HOH:
WATER

ChemComp-NA:
Unknown entry

ChemComp-OLC:
(2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate

ChemComp-AR:
ARGON

Source
  • halobacterium salinarum (strain atcc 700922 / jcm 11081 / nrc-1) (Halophile)
  • dokdonia eikasta (bacteria)
  • candidatus actinomarina minuta (bacteria)
KeywordsMEMBRANE PROTEIN / proton pump / sodium pump / proton pump rhodopsin

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