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Structure paper

TitleAlteration of the Catalytic Reaction Trajectory of a Vicinal Oxygen Chelate Enzyme by Directed Evolution.
Journal, issue, pagesAngew. Chem. Int. Ed. Engl., Vol. 61, Page e202201321-e202201321, Year 2022
Publish dateNov 30, 2021 (structure data deposition date)
AuthorsWang, Y.S. / Zheng, W. / Jiang, N. / Jin, Y.X. / Meng, Z.K. / Sun, M.X. / Zong, Y.L. / Xu, T. / Zhu, J. / Tan, R.X.
External linksAngew. Chem. Int. Ed. Engl. / PubMed:35415958
MethodsX-ray diffraction
Resolution1.5 - 1.8 Å
Structure data

PDB-7w5e:
Oxidase ChaP D49L mutant
Method: X-RAY DIFFRACTION / Resolution: 1.65 Å

PDB-7wb2:
Oxidase ChaP-D49L/Y109F mutant
Method: X-RAY DIFFRACTION / Resolution: 1.8 Å

PDB-7wcc:
Oxidase ChaP-D49L/Q91C mutant
Method: X-RAY DIFFRACTION / Resolution: 1.5 Å

Chemicals

ChemComp-FE:
Unknown entry

ChemComp-HOH:
WATER

Source
  • streptomyces chartreusis (bacteria)
KeywordsBIOSYNTHETIC PROTEIN / Chap / Chartreusin Biosynthesis / Oxidative Rearrangement Steps / OXIDOREDUCTASE / Oxidase / Mycobacterium tuberculosis

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