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TitleMolecular insight into 2-phosphoglycolate activation of the phosphatase activity of bisphosphoglycerate mutase.
Journal, issue, pagesActa Crystallogr D Struct Biol, Vol. 78, Page 472-482, Year 2022
Publish dateJun 1, 2021 (structure data deposition date)
AuthorsAljahdali, A.S. / Musayev, F.N. / Burgner 2nd, J.W. / Ghatge, M.S. / Shekar, V. / Zhang, Y. / Omar, A.M. / Safo, M.K.
External linksActa Crystallogr D Struct Biol / PubMed:35362470
MethodsX-ray diffraction
Resolution2.25 - 2.48 Å
Structure data

PDB-7n3r:
The ternary complex of human Bisphosphoglycerate mutase with 3-phosphoglycerate and 2-phosphoglycolate
Method: X-RAY DIFFRACTION / Resolution: 2.25 Å

PDB-7n3s:
Human bisphosphoglycerate mutase complex with 2-phosphoglycolate
Method: X-RAY DIFFRACTION / Resolution: 2.48 Å

Chemicals

ChemComp-3PG:
3-PHOSPHOGLYCERIC ACID

ChemComp-PGA:
2-PHOSPHOGLYCOLIC ACID

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsISOMERASE / BPGM / Bisphosphoglycerate mutase / 2 / 3-bisphosphoglycerate phosphatase / 3-phosphoglycerate / 2-phosphoglycolate / erythrocyte / activation

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