+Search query
-Structure paper
Title | Covalent Proximity Scanning of a Distal Cysteine to Target PI3K alpha. |
---|---|
Journal, issue, pages | J. Am. Chem. Soc., Vol. 144, Page 6326-6342, Year 2022 |
Publish date | Jun 29, 2021 (structure data deposition date) |
Authors | Borsari, C. / Keles, E. / McPhail, J.A. / Schaefer, A. / Sriramaratnam, R. / Goch, W. / Schaefer, T. / De Pascale, M. / Bal, W. / Gstaiger, M. ...Borsari, C. / Keles, E. / McPhail, J.A. / Schaefer, A. / Sriramaratnam, R. / Goch, W. / Schaefer, T. / De Pascale, M. / Bal, W. / Gstaiger, M. / Burke, J.E. / Wymann, M.P. |
External links | J. Am. Chem. Soc. / PubMed:35353516 |
Methods | X-ray diffraction |
Resolution | 2.69 - 2.85 Å |
Structure data | PDB-7r9v: PDB-7r9y: |
Chemicals | ChemComp-2Q7: ChemComp-2IX: |
Source |
|
Keywords | TRANSFERASE/TRANSFERASE INHIBITOR / PI3K / p110 / PIK3CA / PIP3 / TRANSFERASE / TRANSFERASE-TRANSFERASE INHIBITOR complex |