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TitleOxidative Damage Induces a Vacancy G-Quadruplex That Binds Guanine Metabolites: Solution Structure of a cGMP Fill-in Vacancy G-Quadruplex in the Oxidized BLM Gene Promoter.
Journal, issue, pagesJ. Am. Chem. Soc., Vol. 144, Page 6361-6372, Year 2022
Publish dateDec 29, 2021 (structure data deposition date)
AuthorsWang, K.B. / Liu, Y. / Li, Y. / Dickerhoff, J. / Li, J. / Yang, M.H. / Yang, D. / Kong, L.Y.
External linksJ. Am. Chem. Soc. / PubMed:35352895
MethodsNMR (solution)
Structure data

PDB-7wgw:
NMR Solution Structure of a cGMP Fill-in Vacancy G-quadruplex Formed in the Oxidized BLM Gene Promoter
Method: SOLUTION NMR

Chemicals

ChemComp-PCG:
CYCLIC GUANOSINE MONOPHOSPHATE

Source
  • synthetic construct (others)
KeywordsDNA / 8-oxo-7 / 8-dihydroguanine / G-quadruplex / Bloom syndrome protein / guanine metabolite

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