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Titlel- to d-Amino Acid Substitution in the Immunodominant LCMV-Derived Epitope gp33 Highlights the Sensitivity of the TCR Recognition Mechanism for the MHC/Peptide Structure and Dynamics.
Journal, issue, pagesAcs Omega, Vol. 7, Page 9622-9635, Year 2022
Publish dateJun 29, 2021 (structure data deposition date)
AuthorsBallabio, F. / Broggini, L. / Paissoni, C. / Han, X. / Peqini, K. / Sala, B.M. / Sun, R. / Sandalova, T. / Barbiroli, A. / Achour, A. ...Ballabio, F. / Broggini, L. / Paissoni, C. / Han, X. / Peqini, K. / Sala, B.M. / Sun, R. / Sandalova, T. / Barbiroli, A. / Achour, A. / Pellegrino, S. / Ricagno, S. / Camilloni, C.
External linksAcs Omega / PubMed:35350306
MethodsX-ray diffraction
Resolution2.429 - 2.605 Å
Structure data

PDB-7p0a:
CRYSTAL STRUCTURE OF THE MURINE CLASS I MAJOR HISTOCOMPATIBILITY COMPLEX H-2DB IN COMPLEX WITH LCMV-DERIVED GP33 PEPTIDE with D-AMINOACID (p3P6f)
Method: X-RAY DIFFRACTION / Resolution: 2.429 Å

PDB-7p0t:
CRYSTAL STRUCTURE OF THE MURINE CLASS I MAJOR HISTOCOMPATIBILITY COMPLEX H-2DB IN COMPLEX WITH LCMV-DERIVED GP33 PEPTIDE with D-AMINOACID
Method: X-RAY DIFFRACTION / Resolution: 2.605 Å

Chemicals

ChemComp-SO4:
SULFATE ION

ChemComp-CL:
Unknown entry

ChemComp-HOH:
WATER

Source
  • mus musculus (house mouse)
  • lymphocytic choriomeningitis virus (strain armstrong)
  • lymphocytic choriomeningitis mammarenavirus
KeywordsIMMUNE SYSTEM / D-aminoacid / class I major histocompatibility complex / b2-microglobulin

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