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TitleAntibody-dependent enhancement (ADE) of SARS-CoV-2 pseudoviral infection requires Fc gamma RIIB and virus-antibody complex with bivalent interaction.
Journal, issue, pagesCommun Biol, Vol. 5, Page 262-262, Year 2022
Publish dateNov 22, 2020 (structure data deposition date)
AuthorsWang, S. / Wang, J. / Yu, X. / Jiang, W. / Chen, S. / Wang, R. / Wang, M. / Jiao, S. / Yang, Y. / Wang, W. ...Wang, S. / Wang, J. / Yu, X. / Jiang, W. / Chen, S. / Wang, R. / Wang, M. / Jiao, S. / Yang, Y. / Wang, W. / Chen, H. / Chen, B. / Gu, C. / Liu, C. / Wang, A. / Li, G. / Guo, C. / Liu, D. / Zhang, J. / Zhang, M. / Wang, L. / Gui, X.
External linksCommun Biol / PubMed:35332252
MethodsX-ray diffraction
Resolution2.397 - 3.199 Å
Structure data

PDB-7djz:
Crystal structure of SARS-CoV-2 Spike RBD in complex with MW01 Fab
Method: X-RAY DIFFRACTION / Resolution: 2.397 Å

PDB-7dk0:
Crystal structure of SARS-CoV-2 Spike RBD in complex with MW05 Fab
Method: X-RAY DIFFRACTION / Resolution: 3.199 Å

Chemicals

ChemComp-CIT:
CITRIC ACID

ChemComp-NAG:
2-acetamido-2-deoxy-beta-D-glucopyranose

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
  • severe acute respiratory syndrome coronavirus 2
KeywordsIMMUNE SYSTEM/VIRAL PROTEIN / SARS-CoV-2 / Spike / RBD / Antibody / ADE / VIRUS / IMMUNE SYSTEM-VIRAL PROTEIN complex

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