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Structure paper

TitleDiscovery of APL-1030, a Novel, High-Affinity Nanofitin Inhibitor of C3-Mediated Complement Activation.
Journal, issue, pagesBiomolecules, Vol. 12, Year 2022
Publish dateFeb 4, 2022 (structure data deposition date)
AuthorsGarlich, J. / Cinier, M. / Chevrel, A. / Perrocheau, A. / Eyerman, D.J. / Orme, M. / Kitten, O. / Scheibler, L.
External linksBiomolecules / PubMed:35327625
MethodsX-ray diffraction
Resolution3.4 Å
Structure data

PDB-7tv9:
HUMAN COMPLEMENT COMPONENT C3B IN COMPLEX WITH APL-1030
Method: X-RAY DIFFRACTION / Resolution: 3.4 Å

Chemicals

ChemComp-NAG:
2-acetamido-2-deoxy-beta-D-glucopyranose

Source
  • synthetic construct (others)
  • homo sapiens (human)
KeywordsIMMUNE SYSTEM / complement protein complex

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