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-Structure paper
Title | Retaining the structural integrity of disulfide bonds in diphtheria toxoid carrier protein is crucial for the effectiveness of glycoconjugate vaccine candidates. |
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Journal, issue, pages | Chem Sci, Vol. 13, Page 2440-2449, Year 2022 |
Publish date | Apr 7, 2021 (structure data deposition date) |
Authors | Carboni, F. / Kitowski, A. / Sorieul, C. / Veggi, D. / Marques, M.C. / Oldrini, D. / Balducci, E. / Brogioni, B. / Del Bino, L. / Corrado, A. ...Carboni, F. / Kitowski, A. / Sorieul, C. / Veggi, D. / Marques, M.C. / Oldrini, D. / Balducci, E. / Brogioni, B. / Del Bino, L. / Corrado, A. / Angiolini, F. / Dello Iacono, L. / Margarit, I. / Romano, M.R. / Bernardes, G.J.L. / Adamo, R. |
External links | Chem Sci / PubMed:35310500 |
Methods | X-ray diffraction |
Resolution | 2.03002061079 Å |
Structure data | PDB-7o4w: |
Chemicals | ChemComp-4Y8: ChemComp-EDO: ChemComp-PGE: ChemComp-ACT: ChemComp-HOH: |
Source |
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Keywords | TOXIN / Diphtheria toxin / mutant / disulphide bridge / modified disulphide bridge / acetone. |