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-Structure paper
Title | Arylalkynyl amide-type peroxisome proliferator-activated receptor gamma (PPAR gamma )-selective antagonists covalently bind to the PPAR gamma ligand binding domain with a unique binding mode. |
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Journal, issue, pages | Bioorg. Med. Chem. Lett., Vol. 64, Page 128676-128676, Year 2022 |
Publish date | Jan 22, 2022 (structure data deposition date) |
![]() | Yoshizawa, M. / Aoyama, T. / Itoh, T. / Miyachi, H. |
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Methods | X-ray diffraction |
Resolution | 3.2 Å |
Structure data | ![]() PDB-7wox: |
Chemicals | ![]() ChemComp-5YW: ![]() ChemComp-HOH: |
Source |
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![]() | TRANSCRIPTION / PPARgamma / MTT160 / Covalent modifier / Nuclear Hormone Receptor / Antagonist |