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Structure paper

TitleStructures of PKA-phospholamban complexes reveal a mechanism of familial dilated cardiomyopathy.
Journal, issue, pagesElife, Vol. 11, Year 2022
Publish dateJan 28, 2021 (structure data deposition date)
AuthorsQin, J. / Zhang, J. / Lin, L. / Haji-Ghassemi, O. / Lin, Z. / Woycechowsky, K.J. / Van Petegem, F. / Zhang, Y. / Yuchi, Z.
External linksElife / PubMed:35297759
MethodsX-ray diffraction
Resolution2.162 - 3.43 Å
Structure data

PDB-7e0z:
Crystal structure of PKAc-PLN complex
Method: X-RAY DIFFRACTION / Resolution: 2.162 Å

PDB-7e11:
Crystal structure of PKAc-PLN R9C complex
Method: X-RAY DIFFRACTION / Resolution: 3.43 Å

PDB-7e12:
Crystal structure of PKAc-A11E complex
Method: X-RAY DIFFRACTION / Resolution: 2.796 Å

Chemicals

ChemComp-ANP:
PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER / AMP-PNP, energy-carrying molecule analogue*YM

ChemComp-MG:
Unknown entry

ChemComp-HOH:
WATER

Source
  • mus musculus (house mouse)
  • homo sapiens (human)
KeywordsTRANSFERASE / Kinase / Complex

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