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-Structure paper
Title | Structure of the BAK-activating antibody 7D10 bound to BAK reveals an unexpected role for the alpha 1-alpha 2 loop in BAK activation. |
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Journal, issue, pages | Cell Death Differ., Vol. 29, Page 1757-1768, Year 2022 |
Publish date | Feb 1, 2021 (structure data deposition date) |
Authors | Robin, A.Y. / Miller, M.S. / Iyer, S. / Shi, M.X. / Wardak, A.Z. / Lio, D. / Smith, N.A. / Smith, B.J. / Birkinshaw, R.W. / Czabotar, P.E. ...Robin, A.Y. / Miller, M.S. / Iyer, S. / Shi, M.X. / Wardak, A.Z. / Lio, D. / Smith, N.A. / Smith, B.J. / Birkinshaw, R.W. / Czabotar, P.E. / Kluck, R.M. / Colman, P.M. |
External links | Cell Death Differ. / PubMed:35279694 |
Methods | X-ray diffraction |
Resolution | 3.1 Å |
Structure data | PDB-7lk4: |
Chemicals | ChemComp-MPD: ChemComp-HOH: |
Source |
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Keywords | APOPTOSIS / swap dimer / antibody fragments |