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TitleA Cysteine Variant at an Allosteric Site Alters MIF Dynamics and Biological Function in Homo- and Heterotrimeric Assemblies.
Journal, issue, pagesFront Mol Biosci, Vol. 9, Page 783669-783669, Year 2022
Publish dateNov 18, 2020 (structure data deposition date)
AuthorsSkeens, E. / Pantouris, G. / Shah, D. / Manjula, R. / Ombrello, M.J. / Maluf, N.K. / Bhandari, V. / Lisi, G.P. / Lolis, E.J.
External linksFront Mol Biosci / PubMed:35252348
MethodsX-ray diffraction
Resolution1.6 Å
Structure data

PDB-7kqx:
MIF Y99C homotrimeric mutant
Method: X-RAY DIFFRACTION / Resolution: 1.6 Å

Chemicals

ChemComp-SO4:
SULFATE ION

ChemComp-GOL:
GLYCEROL

ChemComp-IPA:
ISOPROPYL ALCOHOL / alkaloid*YM

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsISOMERASE / MIF / mutant

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