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Structure paper

TitleStructural basis for an unprecedented enzymatic alkylation in cylindrocyclophane biosynthesis.
Journal, issue, pagesElife, Vol. 11, Year 2022
Publish dateJul 31, 2021 (structure data deposition date)
AuthorsBraffman, N.R. / Ruskoski, T.B. / Davis, K.M. / Glasser, N.R. / Johnson, C. / Okafor, C.D. / Boal, A.K. / Balskus, E.P.
External linksElife / PubMed:35212625
MethodsX-ray diffraction
Resolution1.52 - 1.68 Å
Structure data

PDB-7ron:
Crystal structure of the Friedel-Crafts alkylating enzyme CylK from Cylindospermum licheniforme
Method: X-RAY DIFFRACTION / Resolution: 1.68 Å

PDB-7roo:
Crystal structure of Friedel-Crafts alkylating enzyme CylK from Cylindospermum licheniforme with bromide
Method: X-RAY DIFFRACTION / Resolution: 1.52 Å

Chemicals

ChemComp-EDO:
1,2-ETHANEDIOL

ChemComp-CA:
Unknown entry

ChemComp-MG:
Unknown entry

ChemComp-CL:
Unknown entry

ChemComp-HOH:
WATER

ChemComp-BR:
BROMIDE ION

ChemComp-NA:
Unknown entry

Source
  • cylindrospermum licheniforme utex b 2014 (bacteria)
KeywordsTRANSFERASE / beta-propeller / beta-roll / calcium-dependent / alkylation / cylindrocyclophane / halide / Friedel-Crafts

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