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Structure paper

TitleSequence-specific RNA recognition by an RGG motif connects U1 and U2 snRNP for spliceosome assembly.
Journal, issue, pagesProc. Natl. Acad. Sci. USA, Vol. 119, Year 2022
Publish dateJun 29, 2021 (structure data deposition date)
Authorsde Vries, T. / Martelly, W. / Campagne, S. / Sabath, K. / Sarnowski, C.P. / Wong, J. / Leitner, A. / Jonas, S. / Sharma, S. / Allain, F.H.
External linksProc. Natl. Acad. Sci. USA / PubMed:35101980
MethodsNMR (solution) / X-ray diffraction
Resolution1.56 Å
Structure data

PDB-7p08:
Solution structure of the human SF3A1 ubiquitin-like domain
Method: SOLUTION NMR

PDB-7p0v:
Crystal structure of human SF3A1 ubiquitin-like domain in complex with U1 snRNA stem-loop 4
Method: X-RAY DIFFRACTION / Resolution: 1.56 Å

Chemicals

ChemComp-1PE:
PENTAETHYLENE GLYCOL / precipitant*YM

ChemComp-NA:
Unknown entry

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsSPLICING / Spliceosome / U2 snRNP / SF3A / ubiqutin-like domain / RNA BINDING PROTEIN / RGG/RG motif / Intrinsically disordered region

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