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TitleClonally expanded B cells in multiple sclerosis bind EBV EBNA1 and GlialCAM.
Journal, issue, pagesNature, Vol. 603, Page 321-327, Year 2022
Publish dateSep 23, 2020 (structure data deposition date)
AuthorsLanz, T.V. / Brewer, R.C. / Ho, P.P. / Moon, J.S. / Jude, K.M. / Fernandez, D. / Fernandes, R.A. / Gomez, A.M. / Nadj, G.S. / Bartley, C.M. ...Lanz, T.V. / Brewer, R.C. / Ho, P.P. / Moon, J.S. / Jude, K.M. / Fernandez, D. / Fernandes, R.A. / Gomez, A.M. / Nadj, G.S. / Bartley, C.M. / Schubert, R.D. / Hawes, I.A. / Vazquez, S.E. / Iyer, M. / Zuchero, J.B. / Teegen, B. / Dunn, J.E. / Lock, C.B. / Kipp, L.B. / Cotham, V.C. / Ueberheide, B.M. / Aftab, B.T. / Anderson, M.S. / DeRisi, J.L. / Wilson, M.R. / Bashford-Rogers, R.J.M. / Platten, M. / Garcia, K.C. / Steinman, L. / Robinson, W.H.
External linksNature / PubMed:35073561
MethodsX-ray diffraction
Resolution2.5 Å
Structure data

PDB-7k7r:
EBNA1 peptide AA386-405 with Fab MS39p2w174
Method: X-RAY DIFFRACTION / Resolution: 2.5 Å

Chemicals

ChemComp-CL:
Unknown entry

ChemComp-GOL:
GLYCEROL

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
  • human gammaherpesvirus 4 (Epstein-Barr virus)
KeywordsIMMUNE SYSTEM / Autoantigen / EBV / Antibody

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